This study made me curious and I spent a few minutes searching for over-the-counter medications we actually put in our bodies. You always check the back of that bottle of lotion for ingredients, but do you check your suppositories?
Preparation H should be called "Preparation Paraben". Those little suppositories contain both methylparaben and propylparaben.
Children's Tylenol Liquid Contains Butylparaben.
- Parabens are used in some medications and may adversely affect reproduction
- We compare urinary paraben concentrations in relation to medication use
- We control for use of personal care products, an important exposure source
- Paraben-containing medications were associated with increased urinary concentrations
- Paraben-containing medications can be a source of very high paraben exposure
OBJECTIVES
Determine whether paraben-containing medication contributes to high urinary paraben concentrations.
METHODS
Individuals
at a fertility clinic provided multiple urine samples during
evaluation/treatment and reported 24-hour use of medications and
personal care products (PCP). Repeated measures models compared specific
gravity-adjusted urinary methyl, propyl, and butyl paraben
concentrations between samples “exposed” and “unexposed” to
paraben-containing medication.
RESULTS
Eleven
participants contributed 12 exposed and 45 unexposed samples, among
which paraben concentrations did not differ. Use within seven hours was
associated with 8.7-fold and 7.5-fold increases in mean methyl (P=0.11)
and propyl (P=0.10) paraben concentrations, respectively, after
adjusting for PCP use. However, these associations decreased to 1.3-fold
(P=0.76) and 2.6-fold (P=0.34), respectively, after removal of one
influential individual.
CONCLUSION
Paraben-containing medications contributed to higher urinary paraben concentrations within hours of use.
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