Wednesday, June 8, 2016

Eye Opener: Medications as a Source of Paraben Exposure

If you think that you only have to avoid parabens in your makeup and beauty products, think again. The National Institute of Health studied individuals from a fertility clinic to see how taking medication containing parabens impacted the concentration of parabens in their bodies.  It's no surprise that actually ingesting something containing parabens will raise the levels of parabens in your body. You can read more about the study below.

This study made me curious and I spent a few minutes searching for over-the-counter medications we actually put in our bodies. You always check the back of that bottle of lotion for ingredients, but do you check your suppositories? 

Preparation H Hemorrhoidal Cream contains Methylparaben and Propylparaben



Preparation H should be called "Preparation Paraben". Those little suppositories contain both methylparaben and propylparaben.
Children's Tylenol Contains Butylparaben




Children's Tylenol Liquid Contains Butylparaben.








  • Parabens are used in some medications and may adversely affect reproduction
  • We compare urinary paraben concentrations in relation to medication use
  • We control for use of personal care products, an important exposure source
  • Paraben-containing medications were associated with increased urinary concentrations
  • Paraben-containing medications can be a source of very high paraben exposure

OBJECTIVES

Determine whether paraben-containing medication contributes to high urinary paraben concentrations.

METHODS

Individuals at a fertility clinic provided multiple urine samples during evaluation/treatment and reported 24-hour use of medications and personal care products (PCP). Repeated measures models compared specific gravity-adjusted urinary methyl, propyl, and butyl paraben concentrations between samples “exposed” and “unexposed” to paraben-containing medication.

RESULTS

Eleven participants contributed 12 exposed and 45 unexposed samples, among which paraben concentrations did not differ. Use within seven hours was associated with 8.7-fold and 7.5-fold increases in mean methyl (P=0.11) and propyl (P=0.10) paraben concentrations, respectively, after adjusting for PCP use. However, these associations decreased to 1.3-fold (P=0.76) and 2.6-fold (P=0.34), respectively, after removal of one influential individual.

CONCLUSION

Paraben-containing medications contributed to higher urinary paraben concentrations within hours of use.

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